![]() It is currently FDA approved specifically for use in women.While the direct mechanism of pain relief is not known, lubiprostone has been proven to relieve overall IBS symptoms in multiple trials. This leads to increased bowel movement frequency. Lubiprostone (Amitiza®) works through the activation of chloride channels in the bowel.Currently there are 3 FDA approved treatments in this class: lubiprostone, linaclotide, plecanatide, ![]() These drugs also can improve pain, discomfort, and bloating. ![]() Secretagogues/Prosecretory agents are a class of drugs which increase fluid secretion and movement in the GI tract.
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